Description of project:
This postdoctoral project targets the circular recovery of fluorine from poly- and perfluorinated alkyl substances (PFAS)—a class of persistent, toxic environmental pollutants. PFAS are extensively used in industry and consumer products, leading to their widespread presence in water and soil. Their strong carbon–fluorine bonds make them exceptionally resistant to degradation. The project proposes an innovative closed-loop PFAS valorization strategy that integrates advanced defluorination with reuse of fluorine-rich intermediates in pharmaceutical and fine chemical synthesis. It builds on the following objectives
- Photocatalytic and Biocatalytic Degradation of PFAS
Develop and apply photocatalytic and photobiocatalytic approaches to break down fluorinated organic moleculs into smaller, less harmful fluorinated fragments. Emphasis will be placed on technologies such as UV/sulfite systems, electrochemical oxidation, and enzymatic transformations (e.g., fluorinase- or aldolase-based systems).
- Analytical Characterization of PFAS Degradation Products
Utilize advanced analytical methods (e.g., LC-MS/MS, NMR) to monitor PFAS degradation pathways and characterize the generated fluorinated intermediates. Special focus will be on identifying valuable fragments that retain fluorine atoms suitable for further synthetic applications.
- Fluorine Recovery via Chemical and Enzymatic Synthesis
Transform the fluorinated degradation products into high-value compounds through tailored chemical or enzymatic fluorination strategies. This includes applying known fluorinases or engineering novel routes to build reusable fluorinated building blocks, aligning with the principles of green chemistry and circular fluorine economy.
Background:
The project supports the mission of Program 1 and 3 by promoting green materials cycles and biocatalytic synthesis routes. It addresses a critical environmental and regulatory challenge — PFAS contamination — while simultaneously proposing innovative recycling of fluorine for use in drug discovery and specialty chemistry.
Research Objectives:
- Develop novel photocatalytic/biocatalytic systems for PFAS degradation.
- Elucidate transformation pathways and characterize fluorinated intermediates.
- Explore enzymatic methods to incorporate recovered fluorine into value-added chemicals.
- Integrate degradation and synthesis in a holistic fluorine recovery platform.
Methods:
- Experience with homogenous and heterogenous photocatalysis
- Experience with biophotocatalysis desired
- Advanced Oxidation Processes
- Hands-on expertise in LC-MS/MS and NMR for structural elucidation of degradation products
- LC/MS, NMR, FTIR for molecular characterization
- Flow Chemistry or Microreactor Systems
Required skills and qualifications:
We are seeking a candidate with a strong background in photocatalysis and biocatalysis, complemented by advanced analytical skills. Prior international research experience is highly valued, and a publication record commensurate with career stage is expected. The successful applicant will work at the interface of photochemistry and biochemistry in an interdisciplinary environment, take an active role in collaborative projects, and contribute to mentoring, cooperation, and research dissemination.
Main supervisor: Univ.-Prof. Katharina Schröder
Location: TU Wien (Vienna)
Duration: 12 month with option of 36 months, planned start: from March 2026
Submission deadline: 31.01.2026.
Applications can be submitted until: 31st of January 2026
Please send your job application to cb_recruiting@boku.ac.at, indicating your name and the project/position number in the subject line (e.g. “Jane Doe, application for PD 3.10”).
Further information on Application documents and formal criteria see How to apply for PostDoc positions. The application must meet all formal criteria, otherwise it cannot be considered.